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Cattle, Horses, Swine and Sheep - 1 to 2 ml Dogs and Cats - 0.25 to 0.5 ml May be repeated once or twice weekly, as indicated by condition and response

Figure 2 3.1 Activation of inflammatory signaling pathways Research indicates that increased intestinal permeability allows endotoxins such as LPS to enter the systemic circulation, where they trigger systemic inflammatory responses by activating the Toll-like receptor 4/nuclear factor kappa-light-chain-enhancer of activated B cells (TLR4/NF-B) inflammatory pathway

1 2 "The Topol Review NHS Health Education England"